Orange Alert

Michael Marciano

Michael Marciano

Michael Marciano

Professor of Practice and Director for Forensics Research


Forensic Science
1-014 Center for Science and Technology
Office: 315.443.5279






  • Ph.D., Structural Biology, Biochemistry & Biophysics, Syracuse University
  • M.S., Forensic Molecular Biology, State University of New York at Albany
  • B.A., Biology, University of Rochester

Social/Academic Links

Courses Taught

  • FSC 474/674 – Forensic DNA Analysis
  • FSC 440/640 – Forensic Analysis of Biological Evidence
  • FSC 600 – Basic Lab Skills for Advanced Research
Research Interests

Our research focus is at the intersection of genetic identity, DNA based forensic science and issues pertaining to national security. With specific emphasis on the analysis and interpretation of low quality/quantity human and non-human DNA samples using both laboratory techniques and computational tools including machine learning to address problem sets such as DNA mixture interpretation and single cell analyses.

Professional Background

My background as a practicing forensic scientist at the Onondaga County Center for Forensic Sciences has provided a foundation in field based applications of forensic techniques that bridge the gap between practitioners and the research community. I later joined the SRC Inc. Bioforensics group in pursuit of new challenges in applied research and development relating to national security and global threats. I engage the law enforcement, Department of Defense and intelligence communities.

Professional Honors and Memberships
  • New York State Commission on Forensic Science (2021-Present)
  • Patent: Methods and systems for prediction of a DNA profile mixture ratio (U.S. Pat. No. 10854316; 2020)
  • Member of the Organization of Scientific Area Committees (OSAC)– Biological Data Interpretation and Reported Subcommittee (2019-Present)
  • STEM Project of the Year 2017, Technology Alliance of Central New York -PACE: Probabilistic Assessment for Contributor Estimation
  • Patent - Universal DNA profiling (10329609; 2019)
  • American Association of Forensic Sciences, Member
  • Council of Forensic Science Educators, Full Member
Selected Publications
  • Marciano M.A. and Adelman J.D. PACE: Probabilistic Assessment for Contributor Estimation— A machine learning-based assessment of the number of contributors in DNA mixtures. Forensic Science International: Genetics 27 (2017) 82–91.
  • Marciano M.A., Panicker S.X., Liddil G.D., Lindgren D.*, Sweder K.S. Development of a Method to Extract Opium Poppy (Papaver somniferum L.) DNA from Heroin. Nature Scientific Reports 8 (2018) 2590.
  • Williamson V.R.*, Laris T.M.*, Romano R., Marciano M.A. Enhanced DNA Mixture Deconvolution of Sexual Offense Samples Using the DEPArray™ System. Forensic Science International: Genetics. 34(2018) 265-276.
  • Marciano M.A., Williamson V.R.* and Adelman J.D. A Hybrid Approach to Increase the Informedness of CE-based Data Using Locus-Specific Thresholding and Machine Learning. Forensic Science International: Genetics. 35 (2018) 26-37.
  • Adelman, J.D., Zhao A.*, Eberst, D.S*. and Marciano, M.A. (2019) Automated detection and removal of capillary electrophoresis artifacts due to spectral overlap. Electrophoresis, 0, 1-9.
  • Marciano M.A. and Adelman J.D. Developmental Validation of PACE™: Automated Artifact Identification and Contributor Estimation for use with GlobalFiler and PowerPlex® Fusion 6c Generated Data. Forensic Science International: Genetics. 43(2019) 102140.

(*) mentored student

Forensic Science Institute Partners with Leda Health to Explore Feasibility of Early Evidence Sexual Assault Kits

(Aug. 1, 2023)

The self-collection kits would allow survivors of sexual assault to collect their own evidence privately in instances when they don’t have access to a local health care provider.

Forensics Professor Explores New Technology That Could be Gamechanger in Sexual Assault Investigations

(Aug. 9, 2022)

FNSSI’s Mike Marciano is testing a system called DEPArray that has the potential to improve long-held methods of DNA detection.

A&S Forensic Scientists Design the First Machine Learning Approach to Forensic DNA Analysis

(July 15, 2021)

A patent was recently issued to Syracuse University for an invention by Michael Marciano and Jonathan Adelman.

FNSSI’s Mike Marciano Appointed to Committee that Oversees NYS Forensic Lab Accreditation

(April 16, 2021)

Marciano joins a group of crime experts to ensure that forensic work within state and local crime laboratories is conducted accurately.


(Oct. 1, 2019)

Forensics and National Security Sciences Institute Develops DNA Tool

Pinpointing a Perpetrator

(Jan. 23, 2018)

Researchers in the FNSSI are utilizing technology in new ways to bring justice to sexual assault victims

FNSSI Awarded $155,000 Grant from National Institute of Justice

(Oct. 1, 2015)

Researchers will use funds to improve sexual assault investigations

Syracuse to Acquire Cutting-Edge DNA Sequencer

(Aug. 31, 2015)

System will have major implications for forensics teaching, research

Syracuse to Host Training Workshop for DNA Mixture Analysis Software May 11-14

(May 7, 2015)

STRmix workshop reaffirms FNSSI as a national leader in forensics research.

Once Upon a Crime

(Feb. 11, 2015)

Forensic analysis is nothing like it appears on TV, says Syracuse scientist Michael Marciano